Comparative studies in human and armadillo derived Mitsuda lepromin.

This study is o n 2 groups o f leprosy pa t ients using the M i tsuda lepromin test . The first group of 37 pat ients received O · I m l of both human ( Lepromin -H) and Armad i l lo lepromin ( Lepromin-A) i n concentrat ions of 40 m i l l i on baci l l i per m l . The average readings for Lepromin-A and -H were 4 · 7 mm and 2 · I m m respect ively . Using Nested analys is of variance, t h e Lepromin-A readi ngs were found stat ist ica l ly s igni ficant ly ( 2 · 2 t imes) h igher than the Lepromin-H readings. The second group of 60 patients received 40 M baci l l i per m l of Lepromin-A and 1 00 M baci l l i per m l of LeprominH . The average readi ngs for Lepromin-A and H were 6 ·9 mm and 6·3 mm respect ively . This study suggests that with the paucity i n supply of Lepromin -H , Lepromin-A can be used as a good subst i tute i n concentrat ions of 4 0 M baci l l i per m l i n comparison w i t h t h e Lepromin-H using 1 00 M baci l l i per m l .